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Under review simply means the FDA is still assessing: Safety Clinical relevance Regulatory appropriateness It does not mean: The peptide is approved The peptide is widely available The peptide is appropriate for general use At this stage, access to many of these substances may remain limited, inconsistent, or restricted, and quality can vary outside regulated pathways

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However, further studies are needed to investigate the success of uORF targeting in disease models as many of these studies have been proof of principle rather than demonstrating success in disease models